Neita, who lives just 20 minutes down the road from the London Stadium, has the fifth fastest season best in the women's 200m line up, with compatriot Dina Asher-Smith, St Lucia's Julien Alfred and the USA's Gabby Thomas leading the way.
But Neita is ready to soak up the home atmosphere and go up against fierce competition as she gears up for her third Olympic Games this summer.
"It's going to be an amazing race," she said. "The event is going to be great preparation going into the Olympic Games because it's absolute fire and is stacked.
"I need to stick to my race and do what I know I can do.
"It's so special for me, I live 20 minutes from here [the stadium] and it's my favourite track in the world.
"To be running in front of a home crowd ahead of the Olympics will be a great send off."
Neita comes into the event following a silver medal at the 2024 European Championships in Rome, where she missed out on her golden moment by just 0.01 seconds to Switzerland's Mujinga Kambundji.
"To come out of the championships without gold was hard and it took me a while to get over that," she said.
"But I needed that moment which gave me time to reflect and dig deep to make sure I get it right going into the summer. It was probably a blessing in disguise."
World champion Femke Bol put the world on notice last week as she posted a new 400m hurdles European record of 50.95 seconds, the third fastest time in history.
The Dutch athlete now heads to the London Athletics Meet, where she set her previous European record, in the form of her life and over a second faster than the rest of the field.
"I'm really happy and training has also been going great," she said.
"I haven't felt this strong before so there's a good feeling going into the Olympics.
"I'm just focusing on my race and see what time that brings.
"I really love London Diamond League. Last year it was my first time and it was a dream come true.
"I want to put out a good race to show my form and see if I can open up fast and finish stronger. It's one last test before Paris."
Britain's Sammi Kinghorn will be one of the highlights of a stacked women's 800m wheelchair race as she goes head-to-head with 16-time T34 world champion Hannah Cockroft.
Kinghorn is in blistering form this season, setting personal bests from 100m up to 1500m and feels having five para events on the London Athletics Meet schedule was the perfect opportunity to get more eyes on para sport ahead of Paris 2024.
"It's incredibly important to have these events," she said.
"The chance to race in a Diamond League in front of that many thousands of people and on the TV open people's eyes. The London crowd definitely lifts you."
Elsewhere, the USA's Ryan Crouser leads out the men's shot put field after a frustrating year of injury setbacks.
The world record holder injured his elbow at the Indoor World Championships in Glasgow earlier this year, before tearing his peck and re-injuring his elbow in the lead up to his fourth straight US national title.
"It has been a frustrating year to say the least," he said.
"As an athlete, you dream about your preparation for the Olympics going perfectly but I probably did a little overtraining.
"It's been a learning process.
"But I feel good this year now. It has been a limited season but I'm happy with how things are progressing.
"The ultimate goal is the Olympics but there's been a general uphill trend since trials. I can see the light at the end of the tunnel now."
